Polynucleotides are powerful bio-stimulating molecules that support collagen regeneration, improve hydration, and repair damaged skin at a cellular level.

We offer high-quality polynucleotide skin boosters, including top polynucleotide brands known for their proven clinical results. Whether you’re searching for gentle under-eye rejuvenation, full-face revitalization, or targeted treatments for fine lines and texture, our polynucleotide products deliver visible, long-lasting improvements.

Browse our collection, compare polynucleotide reviews, and choose professional-grade solutions that enhance elasticity, firmness, and overall skin health. Upgrade your clinic’s aesthetic treatments with the latest bio-revitalizing technology.

Showing 1–12 of 30 resultsSorted by popularity

ILLUMA Luna 1ml x 1 syringe

£32.99
LUNA is a PN (Polynucleotide) skin booster which is used to treat under and around the eye area. LUNA is a product which hyaluronic acid is added to PN (Polynucleotide), Increasing cell permeability. HA gel is slowly released, increasing the active time of PN and consequently extending the Duration of product efficacy. It has a double boosting effect of regeneration and whitening. ILLUMA LUNA has 5 times more PN (10mg of polynucleotide) than any other product its in category on the market, it also consists of 5mg of Hyaluronic acid.

Aurora RH Collagen

£45.99
Aurora RH Collagen is a recombinant human collagen designed to closely mimic natural human collagen. It provides high purity, consistency, and biocompatibility, making it ideal for applications in regenerative medicine, skincare, and advanced biomaterials.

Lumi Eyes Pro Dermaren 1 X 1ml

£32.99
Lumi Eyes Pro Dermaren is a premium skin booster containing polynucleotides, formulated to hydrate, firm and rejuvenate the delicate under-eye area. This skin booster targets dark circles, puffiness and fine lines for visible brightening and skin quality improvement in a single-syringe professional dose.

AETER Puri Eyes (2%PN 32G 4mm)

£23.99
AETER Puri Eyes is a Polynucleotides Skin Booster, which is meticulously formulated to address the delicate skin around the eyes, optimising skin health and restoring youthfulness.

Plinest Eye Injectable Gel (1 x 2ml)

£62.99
Plinest Eye is an advanced polynucleotide-based injectable gel designed for the delicate under eye area. Plinest Eye works at a cellular level to repair tissue, improve skin quality and diminish under-eye bags and dark circles. The formula stimulates fibroblasts, boosts collagen production and enhances skin elasticity and hydration. The package contains:
  • 2ml syringe
  • 2 x 30G ½” needles.

Lumi-Meso Elite Microneedling Serum

Price range: £20.99 through £83.99
Lumi-Meso Tox is a professional microneedling serum designed to enhance skin smoothness, firmness and overall appearance. Powered by a targeted peptide complex, it helps reduce the appearance of fine lines, wrinkles and skin laxity, promoting a more youthful-looking complexion.

LUMI-PRO Eyes PN Eye Booster | 1ml Per Pack

£27.99
LUMI-PRO Eyes is a cutting-edge skin booster designed to target dark under-eye circles, puffiness, and fine wrinkles.

Nucleofill HAIR (Medium Plus Replacement)

£59.99
Nucleofill HAIR (formerly Nucleofill Medium Plus) is a polynucleotide injectable that is ideal for increasing hair growth and preventing hair loss. Nucleofill HAIR stimulates the hair follicles and improves blood circulation, restoring hair to normal strength, health and thickness. Package contains 1 x 2ml syringe.

Nucleofill 20 (Medium Replacement)

£49.99
Nucleofill 20 (previously Nucleofill Medium) is a bio-stimulating injectable formulated with polynucleotides to minimise signs of ageing. Nucleofill 20 supports skin regeneration and repairs cellular damage so that skin appears more youthful and radiant. Package contains 1 x 1.5ml vial.

NUCLEOFILL AGE 2.5% (STRONG PLUS)

£64.99
Nucleofill AGE 2.5% is a polynucleotide injectable that deeply rejuvenates the skin and combats advanced signs of ageing. Nucleofill AGE protects, renews and hydrates tired, lacklustre skin whilst stimulating collagen production for added elasticity. This treatment is ideal for the face, neck and décolletage. Package contains 1 x 2ml syringe.

Nucleofill SOFT+ CE (EYES)

£59.99
Nucleofill Eyes (Soft Plus) - formally known as Nucleofill Soft Plus - is a polynucleotide-based treatment designed for the under-eye area. This product reduces the appearance of fine lines, wrinkles, dark circles and under-eye bags for a more youthful look. This package contains: 1 x 2ml syringe

Nucleofill Strong CE (25)

£49.99
Nucleofill 25 (formally Nucleofill Strong) is a highly effective polynucleotide (PN) injectable that aids skin rejuvenation and minimises signs of ageing. As a bio-stimulator, Nucleofill 25 promotes cellular regeneration, hydrates dull skin and gradually releases collagen for long-lasting results. Package contains 1 x 1.5ml syringe.

What Is a Polynucleotide Injection & Why Are Clinics Adding It to Their Menus?

Polynucleotide injections are one of the most significant advances in regenerative aesthetics in recent years — and demand from both practitioners and clients continues to grow rapidly. A polynucleotide (PN) is a naturally derived bio-stimulating molecule, typically sourced from highly purified salmon or trout DNA, that works at a cellular level to repair tissue, stimulate collagen and elastin production, and restore deep hydration to ageing or damaged skin. Unlike traditional fillers that physically add volume, polynucleotide injections trigger the skin's own regenerative processes — making them an ideal option for clients seeking natural, progressive improvement rather than immediate structural change. Results typically develop over a course of treatments, with clients noticing improvements in skin tone, texture, firmness, and overall radiance. Treatment areas include the face, neck, décolletage, under-eyes, hands, and scalp — making polynucleotide products one of the most versatile tools in any aesthetic practitioner's toolkit.

Leading Polynucleotide Brands Available at The Hada Filler

We stock a carefully selected range of polynucleotide brands chosen for their clinical efficacy, CE approval, and proven results in professional settings. Our collection includes Nucleofill, available in multiple formulations — Nucleofill 20, Nucleofill Strong CE (25), Nucleofill AGE 2.5%, Nucleofill SOFT+ CE for the under-eye area, and Nucleofill HAIR for scalp and hair rejuvenation. Each variant is designed to target specific concerns and treatment depths, giving practitioners the flexibility to tailor protocols to individual client needs. Alongside Nucleofill, we stock Sunekos 1200 and Sunekos Performa — injectable polynucleotide skin boosters formulated with hyaluronic acid and amino acids to restore the extracellular matrix and improve skin elasticity. For practitioners looking to incorporate advanced brightening and bio-revitalisation into their offering, Mesoheal Pink Glow and the Lumi-Meso microneedling serum range are also available, combining polynucleotide-based technology with skin-brightening actives for multi-action results. Every polynucleotide product in our range is CE-marked, professionally sourced, and stocked with clinic use in mind.

Polynucleotide for UK Aesthetic Professionals

At The Hada Filler, our polynucleotide competitive pricing is designed to support clinics that want to offer high-demand treatments without inflating their cost per treatment. Whether you're building polynucleotide injections into your core treatment menu or introducing them as a complementary add-on alongside skin boosters or dermal fillers, our pricing structure makes it commercially viable from the outset. Single-unit options are available for practitioners trialling new products or treating individual clients, while multi-unit purchasing gives established clinics the cost-per-unit savings needed to run profitable treatment packages. With polynucleotide products typically delivered as a course of two to four sessions, consistent stock availability is essential — and that's exactly what we provide. Fast UK dispatch, reliable stock levels, and a straightforward ordering process mean you can focus on your clients, not your supply chain.

Order Polynucleotide Products Online — Trusted UK Supplier

The Hada Filler is a trusted UK supplier of CE-approved polynucleotide injections for qualified aesthetic professionals. Our online store makes it easy to browse the full range, compare formulations, and place orders in minutes. Whether you're sourcing polynucleotide skin boosters for facial rejuvenation, under-eye treatment, or hair restoration, our range covers every application. Register a professional account today to access competitive pricing and streamline your clinic's ordering process. If you need guidance on which polynucleotide brands best suit your treatment menu, our team is always happy to help — simply get in touch and we'll point you in the right direction.