Polynucleotides are powerful bio-stimulating molecules that support collagen regeneration, improve hydration, and repair damaged skin at a cellular level.

We offer high-quality polynucleotide skin boosters, including top polynucleotide brands known for their proven clinical results. Whether you’re searching for gentle under-eye rejuvenation, full-face revitalization, or targeted treatments for fine lines and texture, our polynucleotide products deliver visible, long-lasting improvements.

Browse our collection, compare polynucleotide reviews, and choose professional-grade solutions that enhance elasticity, firmness, and overall skin health. Upgrade your clinic’s aesthetic treatments with the latest bio-revitalizing technology.

Showing 1–12 of 30 resultsSorted by price: high to low

Pink Glow Mesoheal 10 vials (5ml/vial)

£179.99
Mesoheal PINK GLOW is an advanced whitening cocktail indicated to lighten hyperpigmented areas of the skin and prevent formation of new imperfections on the face and body. The combination of active ingredients in Mesoheal PINK GLOW acts on the process of melanin production in order to achieve a depigmenting, lightening and balancing effect on the skin, thanks to the synergistic and combined action of the active ingredients: 23 types of amino acids, 13 types of vitamins, 6 minerals, 6 coenzymes, 5 nucleic acids, glutathione and hyaluronic acid. PINK GLOW also reduces melanogenic factors, inhibits melanin synthesis and increases cell detoxification, to improve skin’s natural brightness and water levels.

BioRePeelCl3 FND 5 x 6ml

£179.99
BioRePeelCL3 FND is a biphasic peel with 35% trichloroacetic acid (TCA) that revitalises and rejuvenates the skin with minimal downtime. It uses a patented two-phase technology that exfoliates the skin and delivers a blend of acids and vitamins deep into the skin. This package contains: 5 x 6ml

Mastelli NEW Gyn (Gynaecology Item)

£86.99
Suggested to enhance turgor and trophism of skin layers and genital area mucosae
  • 10 mg/ml PN-HPT® (High Purification Technology)
  • 10mg/ml Non-cross linked hyaluronic acid
  • Mannitol
  • Available in 2ml syringe
  • With two 30G ½ needles

SUNEKOS 1200 (2 X 1.5ML VIALS)

£83.99
Sunekos 1200 is an injectable skin booster treatment for severe wrinkles and damaged skin. Formulated with HA and a combination of amino acids, collagen and elastin, this treatment improves facial volume and hydrates the skin. This package contains: 2 x 1.5ml vials.

SUNEKOS Performa (2 x 3.5ml vials)

£83.99
Sunekos Performa is an injectable skin booster recommended for treating blemishes and depressions caused by wrinkles and scars. The treatment acts as a filler, supporting the restoration of physiological elasticity and temporarily replacing volume by expanding the soft tissue. This package contains: 2 x 3.5ml vials

Lumi-Meso Bright Microneedling Serum

Price range: £20.99 through £83.99
Lumi-Meso Bright is a professional microneedling serum designed to support brighter, more even-toned skin and enhanced radiance. Formulated with Tranexamic Acid, Niacinamide, Glutathione and Vitamin C, this serum helps repair sun damage, dark spots and pigmentation.

Lumi-Meso Elite Microneedling Serum

Price range: £20.99 through £83.99
Lumi-Meso Tox is a professional microneedling serum designed to enhance skin smoothness, firmness and overall appearance. Powered by a targeted peptide complex, it helps reduce the appearance of fine lines, wrinkles and skin laxity, promoting a more youthful-looking complexion.

Lumi-Meso Tox Microneedling Serum

Price range: £20.99 through £83.99
Lumi-Meso Tox is an advanced microneedling serum designed to improve skin smoothness, firmness and overall facial appearance. Formulated with a key peptide blend, it targets fine lines, wrinkles and skin laxity, helping to deliver a tighter, more polished complexion.

Plenhyage XL Strong (2.5%)

£71.99
Plenhyage XL Strong is a powerful polynucleotide-based treatment created to rejuvenate the skin. It is a sterile, single-use product intended for injection. Plenhyage XL Strong repairs and regenerates skin by promoting hydration, elasticity and cell turnover. Package contains: 1 x 2ml pre-filled syringe, 2 x 30g ½ needles.

NUCLEOFILL AGE 2.5% (STRONG PLUS)

£64.99
Nucleofill AGE 2.5% is a polynucleotide injectable that deeply rejuvenates the skin and combats advanced signs of ageing. Nucleofill AGE protects, renews and hydrates tired, lacklustre skin whilst stimulating collagen production for added elasticity. This treatment is ideal for the face, neck and décolletage. Package contains 1 x 2ml syringe.

Plinest Hair 1 x 2ml

£62.99
PLINEST Hair 1 x 2ml is a polynucleotide-based injectable gel and can be used for trophic action on the hair and eyebrows. In the form of polymerised polynucleotide-based injectable gels, PLINEST® Hair work by stimulating fibroblasts which encourages cell turnover, improves elasticity, boosts collagen production and hydrates thanks to powerful wound-healing polymers.

Plinest Eye Injectable Gel (1 x 2ml)

£62.99
Plinest Eye is an advanced polynucleotide-based injectable gel designed for the delicate under eye area. Plinest Eye works at a cellular level to repair tissue, improve skin quality and diminish under-eye bags and dark circles. The formula stimulates fibroblasts, boosts collagen production and enhances skin elasticity and hydration. The package contains:
  • 2ml syringe
  • 2 x 30G ½” needles.

What Is a Polynucleotide Injection & Why Are Clinics Adding It to Their Menus?

Polynucleotide injections are one of the most significant advances in regenerative aesthetics in recent years — and demand from both practitioners and clients continues to grow rapidly. A polynucleotide (PN) is a naturally derived bio-stimulating molecule, typically sourced from highly purified salmon or trout DNA, that works at a cellular level to repair tissue, stimulate collagen and elastin production, and restore deep hydration to ageing or damaged skin. Unlike traditional fillers that physically add volume, polynucleotide injections trigger the skin's own regenerative processes — making them an ideal option for clients seeking natural, progressive improvement rather than immediate structural change. Results typically develop over a course of treatments, with clients noticing improvements in skin tone, texture, firmness, and overall radiance. Treatment areas include the face, neck, décolletage, under-eyes, hands, and scalp — making polynucleotide products one of the most versatile tools in any aesthetic practitioner's toolkit.

Leading Polynucleotide Brands Available at The Hada Filler

We stock a carefully selected range of polynucleotide brands chosen for their clinical efficacy, CE approval, and proven results in professional settings. Our collection includes Nucleofill, available in multiple formulations — Nucleofill 20, Nucleofill Strong CE (25), Nucleofill AGE 2.5%, Nucleofill SOFT+ CE for the under-eye area, and Nucleofill HAIR for scalp and hair rejuvenation. Each variant is designed to target specific concerns and treatment depths, giving practitioners the flexibility to tailor protocols to individual client needs. Alongside Nucleofill, we stock Sunekos 1200 and Sunekos Performa — injectable polynucleotide skin boosters formulated with hyaluronic acid and amino acids to restore the extracellular matrix and improve skin elasticity. For practitioners looking to incorporate advanced brightening and bio-revitalisation into their offering, Mesoheal Pink Glow and the Lumi-Meso microneedling serum range are also available, combining polynucleotide-based technology with skin-brightening actives for multi-action results. Every polynucleotide product in our range is CE-marked, professionally sourced, and stocked with clinic use in mind.

Polynucleotide for UK Aesthetic Professionals

At The Hada Filler, our polynucleotide competitive pricing is designed to support clinics that want to offer high-demand treatments without inflating their cost per treatment. Whether you're building polynucleotide injections into your core treatment menu or introducing them as a complementary add-on alongside skin boosters or dermal fillers, our pricing structure makes it commercially viable from the outset. Single-unit options are available for practitioners trialling new products or treating individual clients, while multi-unit purchasing gives established clinics the cost-per-unit savings needed to run profitable treatment packages. With polynucleotide products typically delivered as a course of two to four sessions, consistent stock availability is essential — and that's exactly what we provide. Fast UK dispatch, reliable stock levels, and a straightforward ordering process mean you can focus on your clients, not your supply chain.

Order Polynucleotide Products Online — Trusted UK Supplier

The Hada Filler is a trusted UK supplier of CE-approved polynucleotide injections for qualified aesthetic professionals. Our online store makes it easy to browse the full range, compare formulations, and place orders in minutes. Whether you're sourcing polynucleotide skin boosters for facial rejuvenation, under-eye treatment, or hair restoration, our range covers every application. Register a professional account today to access competitive pricing and streamline your clinic's ordering process. If you need guidance on which polynucleotide brands best suit your treatment menu, our team is always happy to help — simply get in touch and we'll point you in the right direction.